Description
An NIH-supported postdoctoral fellowship is currently available in the Mchaourab laboratory at Vanderbilt University in Nashville, TN. We are a highly interdisciplinary group with interest ranging from proteostasis in zebrafish to the conformational dynamics of active transporters. While historically we were an experimental lab, we have embraced the recent revolution in protein structure prediction and our research platform integrates deep learning methods, such as AlphaFold2, with experimental biophysical approaches to investigate structure/dynamics/function in multiple classes of transporters including ABC transporters and neurotransmitter transporters. Current experimental focus in the lab is on the application of cryo-EM, Electron Paramagnetic Resonance (EPR), transport assays in the context of computational modeling. The laboratory is located in the department of Molecular Physiology and Biophysics at Vanderbilt school of medicine with access to state-of-the-art cores in high performance computing, cryo-EM, EPR, mass spectrometry and various biophysical instrumentation. We are members of the newly inaugurated Center of Applied AI in Protein Dynamics (https://www.vanderbilt.edu/ai-proteindynamics/)
If you are interested send CV and letters of recommendation to: Hassane S. Mchaourab, Ph. D., hassane.mchaourab@vanderbilt.edu
At Vanderbilt University, we are intentional about and assume accountability for fostering advancement and respect for diversity, and inclusion for all students, faculty, and staff. We have created a community that celebrates differences and lets individuality thrive. As part of this commitment, we actively value all aspects of diversity in our workplace and learning environments as we seek to take advantage of the rich backgrounds and abilities of everyone.
Vanderbilt University is an equal opportunity employer. Women, minorities, people with disabilities, and protected veterans are encouraged to apply.
Requirements
Candidates should have a Ph.D. in biochemistry, biophysics or related fields. We strongly welcome candidates with background in computational biology. The training plan will reflect the emerging paradigm of mechanistic structural biology at the interface of computation and experimental sciences. Relevant experimental skills include protein expression and purification, membrane reconstitution, biochemical analyses of function, and structure determination by x-ray crystallography or cryo-EM. Salary will be commensurate with experience and the starting date is negotiable.
