The duties and responsibilities contained in the job description are intended to be examples of the accountabilities for which the person in the position will demonstrate competency through performance. The job description is not intended to be an all-inclusive list. Duties and responsibilities are subject to change and other duties may be assigned as necessary.

Position Summary:

The Feng Laboratory at Sanford Burnham Prebys Medical Discovery Institute invites applications for a highly motivated and passionate Postdoctoral Fellow to join our research team. Our laboratory is dedicated to uncovering the structural and functional mechanisms of disease-related membrane proteins and protein complexes, with a particular focus on endogenous ion channels. In this role, the Postdoctoral Fellow will: Employ cutting-edge cryo-electron microscopy (cryo-EM) to determine high-resolution structures of membrane proteins and protein complexes. Apply a broad range of biochemical and biophysical approaches to investigate protein function and elucidate structurefunction relationships. The successful candidate will become an integral member of a collaborative and supportive research environment, with extensive opportunities for professional development, interdisciplinary collaboration, and scientific growth. Researchers have access to state-of-the-art core facilities on campus, including cryo-EM instrumentation (Titan Krios/K3 and Tecnai T12), biophysics facilities, protein expression and purification resources, and other advanced research infrastructure. This is a fully funded position that offers an excellent opportunity to pursue sustained, high-impact research, develop expertise in structural and functional biology, and generate strong publications.

Duties and Responsibilities:

• Demonstrate knowledge and ability to learn to advance projects
• Generate hypotheses, design experiments, interpret data, trouble shoot and optimize experiments
• Be able to analyze and interpret data from different sources and draw relevant conclusions
• Be able to present results at internal and external meetings
• Accurately document experiments
• Contribute to the writing of reports and manuscripts with increasing responsibility over time
• Work collaboratively across lab functions and train other junior lab staff as needed

Education and/or Experience:

• PhD in Biochemistry, Biophysics, Structural Biology, neuroscience or a related field.
• Experience in cryo-EM imaging and data processing is required
• Experience in protein expression, protein purification, electrophysiological recording or computational biology is advantageous.
• A strong track record of research achievements and excellent communication skills.

Other Knowledge, Skills and/or Abilities:

• Have strong organizational and problem-solving skills
• Excellent data presentation, verbal, and written communication skills
• Possess strong attention to detail, analytical, time management, and interpersonal skills
• Embody the Institute's core values of Commitment, Collaboration, Communication, Community and Compassion
• Provide mentorship to interns and lab members of various skill levels

Supervisory Responsibilities:

Direct: None

Indirect: None